Along with a lot of people, I have a mild case of arachnophobia. I don't go running, screaming like a small child when I see one. But I wouldn't really be happy with one just crawling across my hand or foot, either. I probably wouldn't be too happy about seeing a "large arachnid" like the one being previewed today crawling across my hand or foot, either.
I'd be ok with them crawling around my gaming table, though (in model form). They are six-point Arcanist minions with some staying power (your opponent will need a really big boot to squash them). They sport a fairly decent attack as well as Unimpeded (as one would expect from a spider).