The BYTE RPG is a game system designed to work with a wide range of settings. The new D8-based game book comes with 10 different technology levels and 20 themes that you can mix and match at your desire to create just the setting you want. This new game is up on Kickstarter now.
From the campaign:
The BYTE Roleplaying Game Rulebook stands at over 400 pages, and gives players everything they need to play tabletop RPGs in any setting. The book includes 10 technological levels and 20 thematic modules that can be combined in many unique ways, with each combination creating a different ruleset. This allows the rules to be tailored to the world in which the players want to immerse themselves.
From cowboys to spies, Roman gladiators to mecha pilots, elven knights to vampires, private investigators to galactic rulers, the book provides everything needed for your game. It allows you to play in any historical era or the worlds of your favorite books, movies, series, or video games. It can also easily be customized for use with any "system-agnostic" settings you own.
The campaign's about 3/4 of the way to its goal with 21 days left to go.