From the announcement:
Chrome eyes. Computers called “decks.” Big cyberlimbs and bigger guns. It’s Shadowrun in the year it all started. Take a step back to Shadowrun’s roots with Shadowrun 2050, a book that combines Twentieth Anniversary Edition rules—the smoothest, most accessible rule set Shadowrun has ever had—with the setting that first made the Sixth World a legend.
Shadowrun 2050 has everything players and gamemasters need to dive into the grimy beauty that kicked off one of the greatest roleplaying settings of all times. With information on how to adapt Twentieth Anniversary Edition Matrix, gear, and magic rules for the 2050 setting, as well as in-universe information about the powers of the world, what shadowrunners will be up to, and who they’ll be running into, Shadowrun 2050 puts a new twist on the classic setting.