It's cold and flu season here. You know, you get the sniffles, you grab some orange juice and maybe a swig of cough syrup, then before you know it, you're missing a couple days of work with what feels like the end of the world of sickness. Well, while you may go a little loopy from that cough syrup, it will all pass with time. In Pandemic: Reign of Cthulhu, if you go insane, you might just stay insane.
The Old Ones are trying to make inroads into the real world. It's only by by investigating the location of ancient portals and sealing them away that you can keep this from happening. Pandemic: Reign of Cthulhu takes the "too many fires burning everywhere" feel of Pandemic and gives it an insane twist. Not everyone will be able to be saved, but you and your comrades must do your best, lest the whole world succumb to madness.