For best results, listen to The Eagles while playing.
From the campaign:
In the City: Origins is a fun, dynamic, drafting game for 2-5 players. You take the role of one of the leaders of the city and recruit cards into your faction as you try to control your opponent's options. Each expansion adds new cards, leaders, and concepts to the game increasing the depth of strategy and variety of cards in play.
A drafting game is one in which each player takes turns picking cards from the selection available. In the City: Origins focuses on resource management, increasing selection options, and hurting opponents at crucial moments. This creates interesting game play with lots of replay potential. The In the City series further pushes these boundaries by creating dynamic leader-leader interactions that make leaders both feel different from one another and feel different when playing against particular leaders.