From the campaign:
The World of Darkness is in a downward spiral.
Ecological change is killing off entire species. Wars and atrocities kill of thousands of people every day. Celebrities use their media presence to abuse and violate people who don't feel safe to come forward for decades afterwards. Corporations pay their employees so little that people with jobs need government assistance just to have enough money to stay alive. In the World of Darkness, all of this feeds the Wyrm.