I've really enjoyed a couple deck-builders out there since I tried them at GenCon last year. It's something I'll be looking into.
From the announcement:
I’m the Design Producer for Shadowrun: Crossfire and it’s my pleasure to tell you about this exciting “first ever” for Shadowrun.
Shadowrun: Crossfire is a deck-building game in the style of Dominon or Thunderstone, but it’s also a whole lot more. Shadowrun: Crossfire combines the creative elements of the Shadowrun universe with the feel of adventuring in Shadowrun. You’ll go on runs with your team, engaging in scenarios where your team’s Hacker will be busy manipulating parts of the Matrix, while the Elf Street Samurai is keeping gangers at bay and the Troll Mage is providing support from (and possibly against) the Sixth World.