Prohibition. The US went dry. Of course, you can't really just say, "nobody can drink booze anymore" and that's that. Crime families fond all sorts of way to get hooch to customers. Of course, those crime families sometimes got violent. And that's where you find yourself in Mob: Big Apple, a new board game up on Kickstarter now.
From the campaign:
The campaign's more than 2x funded with 22 days left to go.