He who controls the worms controls the Spice. He who controls the Spice controls... well, you'll have to roll and see if you pass your check first. If you're wanting to dive into the deep lore, political intrigue, and sci-fi action of Dune for yourself, you can as Modiphius has released the PDF version of the Dune RPG's core rulebook.
From the website:
The Dune: Adventures in the Imperium roleplaying game takes you into a far future beyond anything you have imagined, where fear is the mind killer so be sure to keep your wits about you. The Imperium is a place of deadly duels, feudal politics, and mysterious abilities, noble Houses politic constantly for power, influence, and vengeance in a universe where a blade can change the fortunes of millions. Build your House, carve your place in the universe or rebuild an ancient lineage and fight for the Imperial throne.
Take your characters on a journey through the storied worlds of Frank Herbert's sci-fi masterpiece, inhabit elite agents working for noble Houses where Mentats, Swordmasters, Spies, Bene Gesserit Sisters, Devious Advisors, or even desert Fremen join together to follow your banner.
Whoever you choose to be, remember that those that control the spice control the universe.